Here are some suggestions:

• Antwerp’s history: a trip through the historical centre with the cathedral area (possibility of short visit in the cathedral), Vlaaikensgang (an impression of a 16th century inner city), Steen (remnant of the eldest parts of the city) and river Scheldt, Vleeshuis (butchers’ guild hall), Stock Exchange (only during day time) and Market Place.
• In Rubens’ footsteps: with a start at Rubens’ house and workshop, Saint-James’s Church and Rubens’ tomb, Saint-Carl-Borromeus jesuit church, cathedral and end at the feet of the Rubens Statue.
• A students’ town: Ossenmarkt, city campus Antwerp University, Keizerstraat, Saint-Carl-Borromeus jesuit church and Conscience Place, Royal Academy of Fine Arts, town archives, MAS (Museum with a fantastic free aerial view of the town centre).
• Discover bars and beers: visit a few historical ‘brown’ inns and get to know some of the local Belgian beers (do not try to taste all 800 of them in one pass, it won’t do you any good).
• A tour of our historical churches
• The old harbour
• From Central Station to river Scheldt
• …